sacrifice a few bread crumbs to the rat in my kitchen, so he won't nibble at the rest of my food. The rat, once squashed in my trap, gets sacrificed to the gods of fire in my garden, so they'll protect me. The gods of fire, once revealed to be childish superstition, are sacrificed to science, so my universe becomes logical and predictable.
And science? It commands me to sacrifice the idea of a logical and predictable universe, so I'll be no more than an insignificant little crumb, nibbled at by some quantumphysical multidimensional entity.